AstraZeneca Vax Flops Against South African Variant in Early Trial

AstraZeneca’s COVID-19 vaccine was not protective against mild-to-moderate disease from either the so-called South African variant (B.1.351) or the wild type virus, an interim analysis of phase Ib/II data found.

Overall vaccine efficacy against mild-to-moderate COVID-19 in South Africa was 21.9% (95% CI -49.9 to 59.8), and efficacy against B.1.351 was 10.4% (95% CI -76.8 to 54.8), reported Shabir Madhi, PhD, of University of the Witwatersrand in Gauteng, South Africa, and colleagues, in the New England Journal of Medicine.
Source : New England Journal of Medicine